Article
The global population structure and evolutionary history of the acquisition of major virulence factor-encoding genetic elements in Shiga toxin-producing Escherichia coli O121:H19.
Microbial genomics - 1 Dec 2021
Nishida Ruriko, Nakamura Keiji, Taniguchi Itsuki, Murase Kazunori, Ooka Tadasuke, Ogura Yoshitoshi, Gotoh Yasuhiro, Itoh Takehiko, Toyoda Atsushi, Mainil Jacques Georges, Piérard Denis, Seto Kazuko, Harada Tetsuya, Isobe Junko, Kimata Keiko, Etoh Yoshiki, Hamasaki Mitsuhiro, Narimatsu Hiroshi, Yatsuyanagi Jun, Kameyama Mitsuhiro, Matsumoto Yuko, Nagai Yuhki, Kawase Jun, Yokoyama Eiji, Ishikawa Kazuhiko, Shiomoto Takayuki, Lee Kenichi, Kang Dongchon, Akashi Koichi, Ohnishi Makoto, Iyoda Sunao, Hayashi Tetsuya
Abstract excerpt
Shiga toxin (Stx)-producing Escherichia coli (STEC) are foodborne pathogens causing serious diseases, such as haemorrhagic colitis and haemolytic uraemic syndrome. Although O157:H7 STEC strains have been the most prevalent, incidences of STEC infections by several other serotypes have recently increased. O121:H19 STEC is one of these major non-O157 STECs, but systematic whole genome sequence (WGS) analyses have...
Topics
- Animals
- High-Throughput Nucleotide Sequencing
- Humans
- Phylogeny
- Polymorphism, Single Nucleotide
- Prophages
- Serotyping