Article
Left-right asymmetry is formed in individual cells by intrinsic cell chirality.
Mechanisms of development - 1 Aug 2014
Hatori Ryo, Ando Tadashi, Sasamura Takeshi, Nakazawa Naotaka, Nakamura Mitsutoshi, Taniguchi Kiichiro, Hozumi Shunya, Kikuta Junichi, Ishii Masaru, Matsuno Kenji
Abstract excerpt
Many animals show left-right (LR) asymmetric morphology. The mechanisms of LR asymmetric development are evolutionarily divergent, and they remain elusive in invertebrates. Various organs in Drosophila melanogaster show stereotypic LR asymmetry, including the embryonic gut. The Drosophila embryonic hindgut twists 90° left-handedly, thereby generating directional LR asymmetry. We recently revealed that the hindgut...
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