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Article

Epidermal autonomous VEGFA/Flt1/Nrp1 functions mediate psoriasis-like disease.

Science advances - 1 Jan 2020

Benhadou Farida, Glitzner Elisabeth, Brisebarre Audrey, Swedlund Benjamin, Song Yura, Dubois Christine, Rozzi Milena, Paulissen Catherine, Del Marmol Veronique, Sibilia Maria, Blanpain Cédric

Abstract excerpt

Psoriasis is a common chronic skin disorder characterized by keratinocyte hyperproliferation with altered differentiation accompanied by inflammation and increased angiogenesis. It remains unclear whether the first events that initiate psoriasis development occur in keratinocytes or inflammatory cells. Here, using different psoriasis mouse models, we showed that conditional deletion of Flt1 or Nrp1 in epidermal...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 31934626
DOI: 10.1126/sciadv.aax5849
PMCID: PMC6949033

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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