Article
Association between polymorphisms in microRNA seed region and warfarin stable dose.
Postgraduate medical journal - 1 Dec 2020
Hosseindokht Maryam, Zare Hamed, Salehi Rasoul, Pourgholi Leyla, Ziaee Shayan, Boroumand Mohammadali, Sharifi Mohammadreza
Abstract excerpt
BACKGROUND: The optimal dose of anticoagulant warfarin varies among patients to achieve the target international normalised ratio. Although genetic variations related to warfarin pharmacokinetics and vitamin K cycle are important factors associated with warfarin dose requirements, these variations do not completely explain the large interindividual variability observed in the most populations, suggesting that...
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