Article
Non-gradient and genotype-dependent patterns of RSV gene expression.
PloS one - 1 Jan 2020
Piedra Felipe-Andrés, Qiu Xueting, Teng Michael N, Avadhanula Vasanthi, Machado Annette A, Kim Do-Kyun, Hixson James, Bahl Justin, Piedra Pedro A
Abstract excerpt
Respiratory syncytial virus (RSV) is a nonsegmented negative-strand RNA virus (NSV) and a leading cause of severe lower respiratory tract illness in infants and the elderly. Transcription of the ten RSV genes proceeds sequentially from the 3' promoter and requires conserved gene start (GS) and gene end (GE) signals. Previous studies using the prototypical GA1 genotype Long and A2 strains have indicated a gradient...
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