Awareness of genetic risk in the Dominantly Inherited Alzheimer Network (DIAN).

doi:10.1002/alz.12010

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Article

Awareness of genetic risk in the Dominantly Inherited Alzheimer Network (DIAN).

Alzheimer's & dementia : the journal of the Alzheimer's Association - 1 Jan 2020

Aschenbrenner Andrew J, James Bryan D, McDade Eric, Wang Guoqiao, Lim Yen Ying, Benzinger Tammie L S, Cruchaga Carlos, Goate Alison, Xiong Chengjie, Perrin Richard, Buckles Virginia, Allegri Ricardo, Berman Sarah B, Chhatwal Jasmeer P, Fagan Anne, Farlow Martin, O'Connor Antoinette, Ghetti Bernardino, Graff-Radford Neill, Goldman Jill, Gräber Susanne, Karch Celeste M, Lee Jae-Hong, Levin Johannes, Martins Ralph N, Masters Colin, Mori Hiroshi, Noble James, Salloway Stephen, Schofield Peter, Morris John C, Bateman Randall J, Hassenstab Jason

Abstract excerpt

INTRODUCTION: Although some members of families with autosomal dominant Alzheimer's disease mutations learn their mutation status, most do not. How knowledge of mutation status affects clinical disease progression is unknown. This study quantifies the influence of mutation awareness on clinical symptoms, cognition, and biomarkers. METHODS: Mutation carriers and non-carriers from the Dominantly Inherited Alzheimer...

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PMID: 31914221
DOI: 10.1002/alz.12010
PMCID: PMC7206736

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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