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Article

To know or not to know: an update of the literature on the psychological and behavioral impact of genetic testing for Alzheimer disease risk.

Genetic testing and molecular biomarkers - 1 Aug 2012

Rahman Belinda, Meiser Bettina, Sachdev Perminder, Barlow-Stewart Kristine, Otlowski Margaret, Zilliacus Elvira, Schofield Peter

Abstract excerpt

Alzheimer disease (AD) is a genetically heterogenous disorder; in rare cases autosomal dominantly inherited mutations typically cause early-onset familial AD (EOAD), whereas the risk for late-onset AD (LOAD) is generally modulated by genetic variants with relatively low penetrance but high prevalence, with variants in apolipoprotein E (APOE) being a firmly established risk factor. This article presents an...

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Identifiers

PMID: 22731638
DOI: 10.1089/gtmb.2011.0300

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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