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Article

Ferroptosis in Carcinoma: Regulatory Mechanisms and New Method for Cancer Therapy

1 Dec 2019

Abstract excerpt

Ferroptosis is a new form of programmed cell death with characteristic accumulation of reactive oxygen species (ROS) resulting from iron accumulation and lipid peroxidation. Ferroptosis is involved in many diseases, including cancer, and induction of ferroptosis has shown attractive antitumour activities. In this review, we summarize recent findings on the regulatory mechanisms of key regulators of ferroptosis,...

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Identifiers

PMID: 31908494
DOI: 10.2147/ott.s232852

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