Article
Phenotypic Differences in Primary Murine Microglia Treated with NOD1, NOD2, and NOD1/2 Agonists.
Journal of molecular neuroscience : MN - 1 Apr 2020
Wasmuth Susanne, Jalilvand Tida Viola, Laffer Björn, Busch Martin, Bauer Dirk, Langmann Thomas, Thanos Solon, Kasper Maren, Heiligenhaus Arnd
Abstract excerpt
The purpose of the study was studying the influence of different NOD agonists on the morphological phenotype of primary murine microglia and to examine their influence on characteristic cytokines. Primary CD11b-positive cells were isolated from the brain of neonatal mice. The microglial phenotype of the cells was examined by ionized calcium-binding adapter molecule (Iba)1 staining. After14 days in culture, these...
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