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Feline Infectious Peritonitis Virus Nsp5 Inhibits Type I Interferon Production by Cleaving NEMO at Multiple Sites.

Viruses - 30 Dec 2019

Chen Si, Tian Jin, Li Zhijie, Kang Hongtao, Zhang Jikai, Huang Jiapei, Yin Hang, Hu Xiaoliang, Qu Liandong

Abstract excerpt

Feline infectious peritonitis (FIP), caused by virulent feline coronavirus, is the leading infectious cause of death in cats. The type I interferon (type I IFN)-mediated immune responses provide host protection from infectious diseases. Several coronaviruses have been reported to evolve diverse strategies to evade host IFN response. However, whether feline infectious peritonitis virus (FIPV) antagonizes the type...

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Identifiers

PMID: 31905881
DOI: 10.3390/v12010043
PMCID: PMC7019732

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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