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Article

Porcine deltacoronavirus nsp10 antagonizes interferon-β production independently of its zinc finger domains.

Virology - 1 Jul 2021

Fang Puxian, Hong Yingying, Xia Sijin, Zhang Jiansong, Ren Jie, Zhou Yanrong, Fang Liurong, Xiao Shaobo

Abstract excerpt

Porcine deltacoronavirus (PDCoV) is a novel swine enteropathogenic coronavirus that causes serious vomiting and diarrhea in piglets. Previous work demonstrated that PDCoV infection inhibits type I interferon (IFN) production. Here, we found that ectopic expression of PDCoV nsp10 significantly inhibited Sendai virus (SeV)-induced IFN-β production by impairing the phosphorylation and nuclear translocation of two...

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Identifiers

PMID: 33813212
DOI: 10.1016/j.virol.2021.03.015

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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