Article
Encephalomyocarditis Virus Abrogates the Interferon Beta Signaling Pathway via Its Structural Protein VP2.
Journal of virology - 24 Feb 2021
Han Yumei, Xie Jingying, Xu Shujuan, Bi Yingjie, Li Xiangrong, Zhang Haixia, Idris Adi, Bai Jialin, Feng Ruofei
Abstract excerpt
Type I interferon (IFN)-mediated antiviral responses are critical for modulating host-virus responses, and indeed, viruses have evolved strategies to antagonize this pathway. Encephalomyocarditis virus (EMCV) is an important zoonotic pathogen, which causes myocarditis, encephalitis, neurological disease, reproductive disorders, and diabetes in pigs. This study aims to understand how EMCV interacts with the IFN...
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