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Article

Association between rs662 (A > G) and rs854560 (A > T) polymorphisms in PON1 gene and the susceptibility for psoriasis in mestizo population of Western Mexico.

Molecular biology reports - 1 Jan 2021

Hernández-Collazo A A, Pérez-Méndez Oscar, López-Olmos Victoria, Delgado-Rizo V, Muñoz-Valle J F, Martínez-López Erika, Villanueva-Quintero D G, Domínguez-Díaz Carolina, Fafutis-Morris Mary, Alvarado-Navarro Anabell

Abstract excerpt

Psoriasis is a chronic, autoimmune skin disease. In psoriasis, PON1 activity is diminished and peroxidation biomarkers are elevated. The most studied PON1 polymorphisms are rs662 (A > G) and rs854560 (A > T), which have been associated with the antioxidant activity of PON1, risk of cardiovascular diseases and psoriasis development. The aim of this study, was to determine the association of rs662 (A > G) and...

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PMID: 33284416
DOI: 10.1007/s11033-020-06031-z

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