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Article

Haplotype in SERPINA1 (AAT) Is Associated with Reduced Risk for COPD in a Mexican Mestizo Population.

International journal of molecular sciences - 27 Dec 2019

Ponce-Gallegos Marco Antonio, Pérez-Rubio Gloria, García-Carmona Adriana, García-Gómez Jesús, Hernández-Zenteno Rafael, Ramírez-Venegas Alejandra, Falfán-Valencia Ramcés

Abstract excerpt

Protease inhibitor S (PiS) and protease inhibitor Z (PiZ) variants in the SERPINA1 gene are the main genetics factors associated with COPD; however, investigations about other polymorphisms are scanty. The aim of this study was to evaluate two missense single nucleotide polymorphisms (SNPs) (rs709932 and rs1303) in the SERPINA1 gene in Mexican mestizo patients with chronic obstructive pulmonary disease (COPD)...

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Identifiers

PMID: 31892136
DOI: 10.3390/ijms21010195
PMCID: PMC6982076

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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