Article
Genetic Variants in IL6R and ADAM19 are Associated with COPD Severity in a Mexican Mestizo Population.
COPD - 1 Oct 2016
Pérez-Rubio Gloria, Silva-Zolezzi Irma, Fernández-López Juan Carlos, Camarena Ángel, Velázquez-Uncal Mónica, Morales-Mandujano Fabiola, Hernández-Zenteno Rafael De Jesús, Flores-Trujillo Fernando, Sánchez-Romero Candelaria, Velázquez-Montero Alejandra, Espinosa de Los Monteros Carlos, Sansores Raúl H, Ramírez-Venegas Alejandra, Falfán-Valencia Ramcés
Abstract excerpt
Chronic obstructive pulmonary disease (COPD) is a complex and multifactorial disease with a strong genetic component. Our objective is to identify the genetic variants associated with COPD risk and its severity in Mexican Mestizo population. We evaluated 1285 single-nucleotide polymorphisms (SNPs) of candidate genes in 299 smokers with COPD (COPD-S) and 531 smokers without COPD (SWOC) using an Illumina GoldenGate...
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