Article
Genetic variants of BRCA1 and BRCA2 genes in cats with mammary gland carcinoma.
Veterinary and comparative oncology - 1 Jun 2021
Govoni Verônica Mollica, Da Silva Tereza Cristina, Guerra Juliana Mariotti, Pereira Isabel Veloso Alves, Queiroga Felisbina Luisa, Cogliati Bruno
Abstract excerpt
Mammary tumours are the first and third most incident neoplasm in women and cats, respectively. Approximately 85% of feline mammary gland tumours are malignant and aggressive, especially the triple-negative and HER-2+ molecular subtypes. Triple-negative basal-like feline mammary carcinomas (FMCs) are considered suitable models due to the clinical and morphological similarities with human basal-like...
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