Article
Identification of molecular phenotypes in canine mammary carcinomas with clinical implications: application of the human classification.
Virchows Archiv : an international journal of pathology - 1 Aug 2008
Gama A, Alves A, Schmitt F
Abstract excerpt
Similarly to humans, canine mammary cancer represents a heterogeneous group in terms of morphology and biological behaviour. In the present study, we evaluated a series of canine mammary carcinomas based on a new human classification, initially based on gene expression profiling analysis. Similarly to human breast cancer, by using an immunohistochemistry surrogate panel based on five molecular markers [estrogen...
Topics
- Animals
- Cadherins
- Disease-Free Survival
- Dog Diseases
- Dogs
- Female
- Gene Expression Profiling
- Genes, Tumor Suppressor
- Immunohistochemistry
- Kaplan-Meier Estimate
- Keratin-5
