Association between SNP rs1800875, serum chymase and immunoglobulin E levels in patients with coronary heart disease.

doi:10.1631/jzus.B1101008

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Article

Association between SNP rs1800875, serum chymase and immunoglobulin E levels in patients with coronary heart disease.

Journal of Zhejiang University. Science. B - 1 Aug 2011

Jin Chun-Na, Ma Hong, Lin Yan, Wang Jian-An, Xiang Mei-Xiang

Abstract excerpt

OBJECTIVE: The gene for mast cell chymase (CMA1) is an ideal candidate for investigating the genetic predisposition to coronary heart disease (CHD), as activated mast cells have been found to be present in a greater proportion in the shoulder region of atheroma than in normal coronary intimae. Previous studies have indicated that CMA1 promoter polymorphism rs1800875 may be involved in regulating immunoglobulin E...

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Identifiers

PMID: 21796807
DOI: 10.1631/jzus.B1101008
PMCID: PMC3150720

Genes

CMA1

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