Article
Association of AGTR1 and ACE2 gene polymorphisms with structural atrial fibrillation in a Chinese Han population.
Die Pharmazie - 10 Jan 2017
Feng Wei, Sun Lin, Qu Xiu-Fen
Abstract excerpt
The renin-angiotensin system (RAS) is thought to play an important role in atrial fibrillation (AF). The RAS contains the ACE/AngII/AGTR1 axis and the ACE2/Ang(1-7)/MAS axis, which restrict each other via mutual antagonism and regulate myocardial hypertrophy, fibrosis and remodelling. The aim of our study was to investigate the association between single nucleotide polymorphisms (SNPs) in angiotensin-II type-1...
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