Article
Role of m6A RNA methylation in cardiovascular disease (Review).
International journal of molecular medicine - 1 Dec 2020
Qin Yuhan, Li Linqing, Luo Erfei, Hou Jiantong, Yan Gaoliang, Wang Dong, Qiao Yong, Tang Chengchun
Abstract excerpt
N6‑methyladenosine (m6A) is the most prevalent and abundant type of internal post‑transcriptional RNA modification in eukaryotic cells. Multiple types of RNA, including mRNAs, rRNAs, tRNAs, long non‑coding RNAs and microRNAs, are involved in m6A methylation. The biological function of m6A modification is dynamically and reversibly mediated by methyltransferases (writers), demethylases (erasers) and m6A binding...
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