Article
Protective Effect of the MCP-1 Gene Haplotype against Schizophrenia.
BioMed research international - 1 Jan 2019
Saoud Hana, Inoubli Oumaima, Ben Fredj Sihem, Hassine Mohsen, Ben Mohamed Bochra, Gaha Lotfi, Hadj Jrad Besma Bel
Abstract excerpt
While cytokines and their genetic variants have been intensively studied in schizophrenia, little attention has been focused on chemokines in the last years. The monocyte chemoattractant protein 1 (MCP-1) is known to attract peripheral monocytes to the brain during an inflammatory reaction and to affect the T helper (Th) cell development by stimulating Th2 polarization. Owing to the neuroinflammation in...
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