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Article

Involvement of CXCL10 rs4256246, CXCR4 rs2228014, CCR2 rs1799864 and CXCL16 rs2277680 in the Predisposition to Schizophrenia.

Journal of molecular neuroscience : MN - 12 Sept 2024

Saoud Hana, Foddha Hajer, Aflouk Youssef, Jrad Besma Bel Hadj

Abstract excerpt

Chemokine ligands and their receptors have acquired less attention than pro- and anti-inflammatory cytokines in schizophrenia (SCZ). Thus, we aimed to examine the impact of functional polymorphisms of the chemokine genes CXCL10, CXCL16, CXCR4, and CCR2 in the development of SCZ. Using PCR-RFLP, we analyzed the selected polymorphisms in a Tunisian cohort composed of 200 patients with SCZ and 200 healthy controls....

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PMID: 39264476
DOI: 10.1007/s12031-024-02257-9

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