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Article

Zinc transporters maintain longevity by influencing insulin/IGF-1 activity in Caenorhabditis elegans.

FEBS letters - 1 May 2020

Novakovic Stevan, Molesworth Luke W, Gourley Taylin E, Boag Peter R, Davis Gregory M

Abstract excerpt

Adequate dietary intake of essential metals such as zinc is important for maintaining homeostasis. Abnormal zinc intake in Caenorhabditis elegans has been shown to increase or decrease normal lifespan by influencing the insulin/IGF-1 pathway. Distribution of zinc is achieved by a family of highly conserved zinc transport proteins (ZIPT in C. elegans). This study investigated the role of the zipt family of genes...

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PMID: 31883120
DOI: 10.1002/1873-3468.13725

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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