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Article

Zinc mediates the SREBP-SCD axis to regulate lipid metabolism in Caenorhabditis elegans.

Journal of lipid research - 1 Sept 2017

Zhang Jing-Jing, Hao Jun-Jun, Zhang Yu-Ru, Wang Yan-Li, Li Ming-Yi, Miao Hui-Lai, Zou Xiao-Ju, Liang Bin

Abstract excerpt

Maintenance of lipid homeostasis is crucial for cells in response to lipid requirements or surplus. The SREBP transcription factors play essential roles in regulating lipid metabolism and are associated with many metabolic diseases. However, SREBP regulation of lipid metabolism is still not completely understood. Here, we showed that reduction of SBP-1, the only homolog of SREBPs in Caenorhabditis elegans,...

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Zinc
Adipose Tissue
Caenorhabditis elegans
Caenorhabditis elegans Proteins
Genomics

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Lipid Metabolism

Stearoyl-CoA Desaturase

Sterol Regulatory Element Binding Protein 1

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Identifiers

PMID: 28710073
DOI: 10.1194/jlr.M077198
PMCID: PMC5580898

Genes

SCD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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