Article
Utility of hepatic or total body iron burden in the assessment of advanced hepatic fibrosis in HFE hemochromatosis.
Scientific reports - 27 Dec 2019
Chin Justin, Powell Lawrie W, Ramm Louise E, Ayonrinde Oyekoya T, Ramm Grant A, Olynyk John K
Abstract excerpt
Development of advanced hepatic fibrosis in HFE Hemochromatosis (HH) is influenced by hepatic iron concentration (HIC) and age. In patients with HH, it is important to assess the likelihood of cirrhosis and thus the need for confirmatory liver biopsy. Therapeutic phlebotomy also provides an estimate of mobilisable iron stores. We determined whether mobilisable iron stores may predict the presence of advanced...
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