Article
Redox active plasma iron in C282Y/C282Y hemochromatosis.
Blood - 1 Jun 2005
Le Lan Caroline, Loréal Olivier, Cohen Tally, Ropert Martine, Glickstein Hava, Lainé Fabrice, Pouchard Michel, Deugnier Yves, Le Treut André, Breuer William, Cabantchik Z Ioav, Brissot Pierre
Abstract excerpt
Labile plasma iron (LPI) represents the redox active component of non-transferrin-bound iron (NTBI). Its presence in thalassemic patients has been recently reported. The aim of the present study was to quantify LPI in HFE genetic hemochromatosis (GH) and to characterize the mechanisms accounting for its appearance. We studied 159 subjects subdivided into the following groups: (1) 23 with iron overloaded GH; (2)...
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