Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Restoring colistin sensitivity in colistin-resistant E. coli: Combinatorial use of MarR inhibitor with efflux pump inhibitor.

Scientific reports - 25 Dec 2019

Sundaramoorthy Niranjana Sri, Suresh Pavithira, Selva Ganesan Subramaniapillai, GaneshPrasad ArunKumar, Nagarajan Saisubramanian

Abstract excerpt

Antibiotics like colistin are the last resort to deal with infections by carbapenem-resistant Enterobacteriaceae (CREB). Resistance to colistin severely restricts therapeutic options. To tackle this dire situation, urgent measures to restore colistin sensitivity are needed. In this study, whole-genome sequencing of colistin-resistant E. coli strain was performed and the genome analysis revealed that the strain...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anti-Bacterial Agents
Share to Carbapenem-Resistant Enterobacteriaceae

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Colistin

Share to Drug Resistance, Bacterial

Share to Escherichia coli Proteins

Share to Microbial Sensitivity Tests

Share to Repressor Proteins

Share to Salicylates

Source

Open in PubMed Open full text

Identifiers

PMID: 31882661
DOI: 10.1038/s41598-019-56325-x
PMCID: PMC6934491

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Restoring colistin sensitivity in colistin-resistant E. coli: Combinatorial use of MarR inhibitor with efflux pump inhibitor.PMID 31882661Read ↗

Valnemulin restores colistin sensitivity against multidrug-resistant gram-negative pathogensSemantic proximity Read ↗

Current Update on Intrinsic and Acquired Colistin Resistance Mechanisms in BacteriaSemantic proximity Read ↗

Colistin Resistance Mechanism and Management Strategies of Colistin-Resistant <em>Acinetobacter baumannii</em> InfectionsSemantic proximity Read ↗

Colistin Resistance Mechanism and Management Strategies of Colistin-Resistant Acinetobacter baumannii InfectionsSemantic proximity Read ↗

Small Molecule Adjuvants Potentiate Colistin Activity and Attenuate Resistance Development in Escherichia coli by Affecting pmrAB SystemSemantic proximity Read ↗

Understanding Recent Developments in Colistin Resistance: Mechanisms, Clinical Implications, and Future PerspectivesSemantic proximity Read ↗

In vivo Emergence of Colistin Resistance in Carbapenem-Resistant Klebsiella pneumoniae Mediated by Premature Termination of the mgrB Gene RegulatorSemantic proximity Read ↗

Efflux pump inhibitor CCCP to rescue colistin susceptibility in mcr-1 plasmid-mediated colistin-resistant strains and Gram-negative bacteriaSemantic proximity Read ↗

Non-clonal emergence of colistin resistance associated with mutations in the BasRS two-component system in <i>Escherichia coli</i> bloodstream isolatesSemantic proximity Read ↗

Antimicrobial resistance during COVID-19 pandemic: alternatives to combat bacterial infections.Semantic proximity Read ↗

Harder, better, faster, stronger: Colistin resistance mechanisms in Escherichia coliSemantic proximity Read ↗

Diclofenac sensitizes multi-drug resistant <i>Acinetobacter baumannii</i> to colistinSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.