Article
In-silico Analyses of Disease Causing Mutations in SLURP1 Gene.
Annals of clinical and laboratory science - 1 Nov 2019
Jafar Hussain Hafiz Muhammad, Khan Ranjha, Li Chunyi, Aftab Ayesha, Muneer Iqra, Wahab Fazal, Wu Limin, Jiang Xiaohua, Xu Peng
Abstract excerpt
The SLURP1 (secreted LY6/urokinase type plasminogen activator receptor related protein-1) belongs to the gene family of urokinase, a type of plasminogen activator receptor (uPAR). Mutations in the SLURP1 have been reported to cause serious genetic problems of skin, Mal De Meleda, and malignancies. With the advancement of computational tools, it became possible to predict the potential impact of gene variants on...
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