Article

Novel <i>mutations within</i> PRSS1 Gene that could potentially cause hereditary pancreatitis: Using Comprehensive in silico Approach

2019-01-14

Abstract excerpt

<h4>Background</h4> Hereditary pancreatitis (HP) is an autosomal dominant disorder with incomplete penetrance characterized by recurring episodes of severe abdominal pain often presenting in childhood. The comprehensive in silico analysis of coding SNPs, and their functional impacts on protein level, still remains unknown. In this study, we aimed to identify the pathogenic SNPs in PRSS1 gene by computational an...

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Literature Corpus work: 94f2833f-a8aa-5b5e-ae85-8b0288302a97
DOI: 10.1101/519926

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