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Article

The effect of childhood trauma, ApoE genotype and HIV-1 viral protein R variants on change in cognitive performance.

BMC research notes - 27 Dec 2019

Womersley Jacqueline S, Clauss Lara B, Varathan Olivette, Engelbrecht Susan, Hemmings Sian M J, Seedat Soraya, Spies Georgina

Abstract excerpt

OBJECTIVE: Gene-environment interactions contribute to the development of HIV-associated neurocognitive disorders. We examined whether childhood trauma, apolipoprotein E isoforms and viral protein R (Vpr) variants were associated with change in cognitive performance. Seventy-three seropositive women completed neuropsychological assessments at baseline and 1-year follow-up. We conducted genetic analyses using DNA...

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Identifiers

PMID: 31881924
DOI: 10.1186/s13104-019-4869-9
PMCID: PMC6935155

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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