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Article

Gene-environment interaction of ApoE genotype and combat exposure on PTSD.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 1 Oct 2013

Lyons Michael J, Genderson Margo, Grant Michael D, Logue Mark, Zink Tyler, McKenzie Ruth, Franz Carol E, Panizzon Matthew, Lohr James B, Jerskey Beth, Kremen William S

Abstract excerpt

Factors determining who develops PTSD following trauma are not well understood. The €4 allele of the apolipoprotein E (apoE) gene is associated with dementia and unfavorable outcome following brain insult. PTSD is also associated with dementia. Given evidence that psychological trauma adversely affects the brain, we hypothesized that the apoE genotype moderates effects of psychological trauma on PTSD...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24132908
DOI: 10.1002/ajmg.b.32154
PMCID: PMC4745646

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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