Article
Evaluation of polymorphisms in microRNA-binding sites and pancreatic cancer risk in Chinese population.
Journal of cellular and molecular medicine - 1 Feb 2020
Ke Juntao, Peng Xiating, Mei Shufang, Tian Jianbo, Ying Pingting, Yang Nan, Wang Xiaoyang, Zou Danyi, Yang Yang, Zhu Ying, Gong Yajie, Gong Jing, Zhong Rong, Chang Jiang, Fang Zemin, Miao Xiaoping
Abstract excerpt
As promising biomarkers and therapy targets, microRNAs (miRNAs) are involved in various physiological and tumorigenic processes. Genetic variants in miRNA-binding sites can lead to dysfunction of miRNAs and contribute to disease. However, systematic investigation of the miRNA-related single nucleotide polymorphisms (SNPs) for pancreatic cancer (PC) risk remains elusive. We performed integrative bioinformatics...
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