Article
rs1859168 A > C polymorphism regulates HOTTIP expression and reduces risk of pancreatic cancer in a Chinese population.
World journal of surgical oncology - 17 Aug 2017
Hu Pinghai, Qiao Ou, Wang Jun, Li Jiao, Jin Hao, Li Zhaolian, Jin Yan
Abstract excerpt
BACKGROUND: Long non-coding RNAs (lncRNAs) are aberrantly expressed in many types of human cancer including pancreatic cancer (PC) and correlated with tumorigenesis and cancer prognosis, whereas knowledge about regulatory mechanism of lncRNA expression is few known. This study aimed to explore whether polymorphisms in lncRNAs genes are associated with PC susceptibility by affecting its expression. METHODS: We...
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