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Article

AlleleProfileR: A versatile tool to identify and profile sequence variants in edited genomes.

PloS one - 1 Jan 2019

Bruyneel Arne A N, Colas Alexandre R, Karakikes Ioannis, Mercola Mark

Abstract excerpt

Gene editing strategies, such as zinc-finger nucleases (ZFNs), transcription activator-like effector nucleases (TALENs), and clustered regularly interspaced short palindromic repeat/Cas9 (CRISPR/Cas9), are revolutionizing biology. However, quantitative and sensitive detection of targeted mutations are required to evaluate and quantify the genome editing outcomes. Here we present AlleleProfileR, a new analysis...

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Identifiers

PMID: 31877162
DOI: 10.1371/journal.pone.0226694
PMCID: PMC6932767

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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