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Article

Comparison of somatic variant detection algorithms using Ion Torrent targeted deep sequencing data.

BMC medical genomics - 24 Dec 2019

Wang Qing, Kotoula Vassiliki, Hsu Pei-Chen, Papadopoulou Kyriaki, Ho Joshua W K, Fountzilas George, Giannoulatou Eleni

Abstract excerpt

BACKGROUND: The application of next-generation sequencing in cancer has revealed the genomic landscape of many tumour types and is nowadays routinely used in research and clinical settings. Multiple algorithms have been developed to detect somatic variation from sequencing data using either paired tumour-blood or tumour-only samples. Most of these methods have been developed and evaluated for the identification...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 31874647
DOI: 10.1186/s12920-019-0636-y
PMCID: PMC6929331

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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