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Article

RNA editing-based classification of diffuse gliomas: predicting isocitrate dehydrogenase mutation and chromosome 1p/19q codeletion.

BMC bioinformatics - 24 Dec 2019

Chen Sean Chun-Chang, Lo Chung-Ming, Wang Shih-Hua, Su Emily Chia-Yu

Abstract excerpt

BACKGROUND: Accurate classification of diffuse gliomas, the most common tumors of the central nervous system in adults, is important for appropriate treatment. However, detection of isocitrate dehydrogenase (IDH) mutation and chromosome1p/19q codeletion, biomarkers to classify gliomas, is time- and cost-intensive and diagnostic discordance remains an issue. Adenosine to inosine (A-to-I) RNA editing has emerged as...

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Identifiers

PMID: 31870275
DOI: 10.1186/s12859-019-3236-0
PMCID: PMC6929429

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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