LRRK2 Biology from structure to dysfunction: research progresses, but the themes remain the same.

Abstract excerpt

Since the discovery of leucine-rich repeat kinase 2 (LRRK2) as a protein that is likely central to the aetiology of Parkinson's disease, a considerable amount of work has gone into uncovering its basic cellular function. This effort has led to the implication of LRRK2 in a bewildering range of cell biological processes and pathways, and probable roles in a number of seemingly unrelated medical conditions. In this...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Autophagy
• Share to Leucine-Rich Repeat Serine-Threonine Protein Kinase-2