The mitochondrial genome, a growing interest inside an organelle.

doi:10.2147/ijn.s2482

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Article

The mitochondrial genome, a growing interest inside an organelle.

International journal of nanomedicine - 1 Jan 2008

Crimi Marco, Rigolio Roberta

Abstract excerpt

Mitochondria are semi-autonomously reproductive organelles within eukaryotic cells carrying their own genetic material, called the mitochondrial genome (mtDNA). Until some years ago, mtDNA had primarily been used as a tool in population genetics. As scientists began associating mtDNA mutations with dozens of mysterious disorders, as well as the aging process and a variety of chronic degenerative diseases, it...

Topics

Animals
DNA, Mitochondrial
Genetic Predisposition to Disease
Genome, Mitochondrial
Humans
Mitochondrial Diseases
Models, Genetic

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Identifiers

PMID: 18488415
DOI: 10.2147/ijn.s2482
PMCID: PMC2526360

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