Article
PlexinB1 Promotes Nuclear Translocation of the Glucocorticoid Receptor.
Cells - 18 Dec 2019
Williamson Magali, Garg Ritu, Wells Claire M
Abstract excerpt
Androgen receptor (AR) and glucocorticoid receptor (GR) are nuclear receptors whose function depends on their entry into the nucleus where they activate transcription of an overlapping set of genes. Both AR and GR have a role in resistance to androgen deprivation therapy (ADT), the mainstay of treatment for late stage prostate cancer. PlexinB1, a receptor for semaphorins, has been implicated in various cancers...
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