Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Preliminary investigation on the molecular mechanisms underlying the correlation between VDR-FokI genotype and periodontitis.

Journal of periodontology - 1 Mar 2020

Liu Kaining, Han Bing, Hou Jianxia, Meng Huanxin

Abstract excerpt

BACKGROUND: The only polymorphism that could change the protein structure in vitamin D receptor (VDR) is the FokI polymorphism (rs2228570). The FF genotype has the strongest transcriptional activity of VDR and is correlated with higher susceptibility to periodontitis. To reveal the possible molecular mechanisms for the correlation preliminarily, the influence of VDR-FokI genotype on the expression of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gingiva

Share to Periodontal Ligament

Share to Periodontitis

Share to Receptors, Calcitriol

Source

Identifiers

PMID: 31859389
DOI: 10.1002/JPER.19-0368

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Preliminary investigation on the molecular mechanisms underlying the correlation between VDR-FokI genotype and periodontitis.PMID 31859389Read ↗

Influence of rs2228570 on Transcriptional Activation by the Vitamin D Receptor in Human Gingival Fibroblasts and Periodontal Ligament Cells.Semantic proximity Read ↗

[Influence of vitamin D receptor FokI polymorphism on expression of CYP24A1 in periodontal cells].Semantic proximity Read ↗

Vitamin D Binding Protein and Receptor Prevalence in a Large Population with Periodontitis: Genetic Polymorphisms and Transcriptomic ProfilingSemantic proximity Read ↗

Vitamin D binding protein and receptor prevalence in a large population with periodontitis: single nucleotide polymorphism and transcriptomic profiling.Semantic proximity Read ↗

BsmI, TaqI, ApaI, and FokI polymorphisms in the vitamin D receptor gene and periodontitis: a meta-analysis of 15 studies including 1338 cases and 1302 controls.Semantic proximity Read ↗

The association between vitamin D receptor FokI gene polymorphism and osteoporosis in postmenopausal women: a meta-analysis.Semantic proximity Read ↗

FokI polymorphism in vitamin D receptor gene: Differential expression of TNFα in peripheral mononuclear cells of type 2 diabetic subjectsSemantic proximity Read ↗

Interplay between vitamin D receptor FokI polymorphism and smoking influences Porphyromonas gingivalis proportions in subgingival plaque.Semantic proximity Read ↗

Effects of Fok-I polymorphism in vitamin D receptor gene on serum 25-hydroxyvitamin D, bone-specific alkaline phosphatase and calcaneal quantitative ultrasound parameters in young adults.Semantic proximity Read ↗

Association between vitamin D receptor gene haplotypes and chronic periodontitis among Japanese men.Semantic proximity Read ↗

Association between vitamin D receptor gene polymorphisms and severe chronic periodontitis in a Chinese population.Semantic proximity Read ↗

Vitamin D Receptor Gene Polymorphism as a Risk Factor for Chronic PeriodontitisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.