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FokI polymorphism in vitamin D receptor gene: Differential expression of TNFα in peripheral mononuclear cells of type 2 diabetic subjects

2 Nov 2015

Abstract excerpt

FokI polymorphism has been associated with obesity and type 2 diabetes (T2D) in some populations. To investigate the frequencies of a genetic polymorphism of Vitamin D receptor (FokI) in patients with T2D and control subjects and investigate the role of 1,25(OH)2D3 in the expression of pro-inflammatory markers in peripheral blood mononuclear cells (PBMCs). The case–control study was conducted in 160 patients with...

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PMID: 30941281
DOI: 10.1016/j.mgene.2015.10.003

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