Article
[Influence of vitamin D receptor FokI polymorphism on expression of CYP24A1 in periodontal cells].
Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences - 18 Feb 2018
Liu K N, Meng H X, Hou J X
Abstract excerpt
OBJECTIVE: There is asingle nucleotide polymorphism (SNP) in the exon 2 of the vitamin D receptor (VDR) gene that can be distinguished using the restriction endonuclease FokI, and accordingly divided into three genotypes: FF, Ff and ff. VDR-FokI polymorphism was the only known SNP that could alter the protein structure of VDR. CYP24A1 is the gene encoding vitamin D 24 hydroxylase and is a vitamin D responsive...
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