Article
What Does Chronic Myeloid Leukaemia Tell Us About Other Leukaemias?
Current hematologic malignancy reports - 1 Dec 2019
Gale Robert Peter, Apperley Jane
Abstract excerpt
PURPOSE OF REVIEW: Determine if therapy of chronic myeloid leukaemia (CML) is a model for treating other cancers. RECENT FINDINGS: CML has a relatively homogeneous phenotype and genotype and is caused by one mutation, BCRABL1, in every instance. In contrast, most other leukaemias, haematologic cancers and solid cancer have more heterogeneous phenotypes and extraordinarily greater genotypic diversity and...
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