Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Heterogeneity of molecular markers in chronic myelomonocytic leukemia: a disease associated with several gene alterations.

Cellular and molecular life sciences : CMLS - 1 Sept 2012

Bastie Jean-Noël, Aucagne Romain, Droin Nathalie, Solary Eric, Delva Laurent

Abstract excerpt

The relatively homogenous clinical features and poor prognosis of chronic myelomonocytic leukemia (CMML) are associated with a molecular heterogeneity, with various mutations impacting several convergent pathways. Due to the restricted understanding of the mechanism involved in leukemogenesis, CMML still appears as a diagnostic and therapeutic undertaking, and poor prognosis of leukemia. Contrary to chronic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biomarkers, Tumor
Share to ABL1 gene

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to BCR gene

Share to Genetic Variation

Share to Leukemia, Myelomonocytic, Chronic

Share to Neoplasm Proteins

Share to Oncogene Proteins, Fusion

Source

Open in PubMed Open full text

Identifiers

PMID: 22415325
DOI: 10.1007/s00018-012-0956-y
PMCID: PMC11114957

Genes

ABL1
BCR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Heterogeneity of molecular markers in chronic myelomonocytic leukemia: a disease associated with several gene alterations.PMID 22415325Read ↗

Chronic Myelomonocytic Leukemia: Insights into Biology, Prognostic Factors, and Treatment.Semantic proximity Read ↗

[Chronic myelomonocytic leukemia (CMML): recent advances in molecular pathogenesis and treatment].Semantic proximity Read ↗

When clinical heterogeneity exceeds genetic heterogeneity: thinking outside the genomic box in chronic myelomonocytic leukemia.Semantic proximity Read ↗

Evolving Understanding of Chronic Myelomonocytic Leukemia: Implications for Future Treatment Paradigms.Semantic proximity Read ↗

Chronic myelomonocytic leukaemia: a concise clinical and pathophysiological reviewSemantic proximity Read ↗

Genetic complexity of chronic myelomonocytic leukemia.Semantic proximity Read ↗

Chronic myelomonocytic leukemia: myeloproliferative variant.Semantic proximity Read ↗

Prognostic implications of genetic aberrations in acute myelogenous leukemia with normal cytogenetics.Semantic proximity Read ↗

Outcomes and molecular profile of oligomonocytic CMML support its consideration as the first stage in the CMML continuum.Semantic proximity Read ↗

Molecular characterization of acute myeloid leukemia and its impact on treatment.Semantic proximity Read ↗

Molecular and prognostic correlates of cytogenetic abnormalities in chronic myelomonocytic leukemia: a Mayo Clinic-French Consortium Study.Semantic proximity Read ↗

Mixed phenotype acute leukemia contains heterogeneous genetic mutations by next-generation sequencingSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.