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Article

Leukaemias into the 21st century: part 1: the acute leukaemias.

Internal medicine journal - 1 Nov 2012

Brown C M S, Larsen S R, Iland H J, Joshua D E, Gibson J

Abstract excerpt

The leukaemias are a biologically and clinically heterogeneous group of malignancies, which manifest as clonal expansions of a single cell at different stages of lympho-haemopoietic development. The transformed cell acquires an unrestrained capacity for self-renewal and, in the case of the acute leukaemias, also fails to differentiate into functional mature cells. Historically leukaemias were classified using a...

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Identifiers

PMID: 23157517
DOI: 10.1111/j.1445-5994.2012.02938.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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