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Article

TopControl: A Tool to Prioritize Candidate Disease-associated Genes based on Topological Network Features.

Scientific reports - 19 Dec 2019

Nazarieh Maryam, Helms Volkhard

Abstract excerpt

Putative disease-associated genes are often identified among those genes that are differentially expressed in disease and in normal conditions. This strategy typically yields thousands of genes. Gene prioritizing schemes boost the power of identifying the most promising disease-associated genes among such a set of candidates. We introduce here a novel system for prioritizing genes where a TF-miRNA co-regulatory...

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Identifiers

PMID: 31857653
DOI: 10.1038/s41598-019-55954-6
PMCID: PMC6923402

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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