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Article

Global Prioritizing Disease Candidate lncRNAs via a Multi-level Composite Network.

Scientific reports - 4 Jan 2017

Yao Qianlan, Wu Leilei, Li Jia, Yang Li Guang, Sun Yidi, Li Zhen, He Sheng, Feng Fangyoumin, Li Hong, Li Yixue

Abstract excerpt

LncRNAs play pivotal roles in many important biological processes, but research on the functions of lncRNAs in human disease is still in its infancy. Therefore, it is urgent to prioritize lncRNAs that are potentially associated with diseases. In this work, we developed a novel algorithm, LncPriCNet, that uses a multi-level composite network to prioritize candidate lncRNAs associated with diseases. By integrating...

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Identifiers

PMID: 28051121
DOI: 10.1038/srep39516
PMCID: PMC5209722

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