Article
The genomic landscape of Mexican Indigenous populations brings insights into the peopling of the Americas.
Nature communications - 12 Oct 2021
García-Ortiz Humberto, Barajas-Olmos Francisco, Contreras-Cubas Cecilia, Cid-Soto Miguel Ángel, Córdova Emilio J, Centeno-Cruz Federico, Mendoza-Caamal Elvia, Cicerón-Arellano Isabel, Flores-Huacuja Marlen, Baca Paulina, Bolnick Deborah A, Snow Meradeth, Flores-Martínez Silvia Esperanza, Ortiz-Lopez Rocio, Reynolds Austin W, Blanchet Antonio, Morales-Marín Mirna, Velázquez-Cruz Rafael, Kostic Aleksandar David, Galaviz-Hernández Carlos, García-Zapién Alejandra Guadalupe, Jiménez-López José Concepción, León-Reyes Guadalupe, Salas-Bautista Eva Gabriela, Lazalde-Ramos Blanca Patricia, Jiménez-Ruíz Juan Luis, Salas-Martínez Guadalupe, Ramos-Madrigal Jazmín, Mirzaeicheshmeh Elaheh, Saldaña-Alvarez Yolanda, Del Carmen Abrahantes-Pérez María, Loeza-Becerra Francisco, Mojica-Espinosa Raúl, Sánchez-Quinto Federico, Rangel-Villalobos Héctor, Sosa-Macías Martha, Sánchez-Corona José, Rojas-Martinez Augusto, Martínez-Hernández Angélica, Orozco Lorena
Abstract excerpt
The genetic makeup of Indigenous populations inhabiting Mexico has been strongly influenced by geography and demographic history. Here, we perform a genome-wide analysis of 716 newly genotyped individuals from 60 of the 68 recognized ethnic groups in Mexico. We show that the genetic structure of these populations is strongly influenced by geography, and our demographic reconstructions suggest a decline in the...
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