The evolutionary history and unique genetic diversity of Indigenous Americans.

doi:10.1038/s41586-026-10406-w

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

The evolutionary history and unique genetic diversity of Indigenous Americans.

Nature - 1 May 2026

Castro E Silva Marcos Araújo, Nunes Kelly, Ribeiro Maíra R, Passarelli-Araujo Hemanoel, Lemes Renan Barbosa, Kimura Lilian, Sacuena Putira, G Amorim Carlos Eduardo, Bortolini Maria Cátira, Mill José Geraldo, Guerreiro João Farias, Barbieri Chiara, Hernández-Zaragoza Diana Iraíz, Walter Antonia, Chowdhury Trija Nag, Macías-Herrera Daniela, Lara-Riegos Julio César, Del Castillo-Chávez Oana, Zurita Camilo, Tito-Álvarez Ana María, Vásquez-Domínguez Emilia, Moo-Mezeta María Ermila, Torres-Romero Julio César, Aguilar-Campos Abraham, Serrano-Osuna Ricardo, Parolín Maria Laura, Bravi Claudio M, Ramallo Virgínia, Bailliet Graciela, Revollo Susana, Sandoval José R, Fujita Ricardo, Barquera Rodrigo, Santos Fabrício R, Comas David, Hünemeier Tábita

Abstract excerpt

Indigenous peoples of America represent the last principal expansion of humans across the globe1, yet their genetic history remains one of the least explored2. Although these populations have inhabited the continent for thousands of years3, their evolutionary history remains largely unresolved4,5, owing to the limited availability of genomic data. Here we present data on 128 high-coverage Indigenous American...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetics, Population

Share to Genome, Human

Share to Human Migration

Share to Indians, North American

Share to Indians, South American

Share to Reproduction

Share to Selection, Genetic

Share to South America

Source

Open in PubMed Open full text

Identifiers

PMID: 42020734
DOI: 10.1038/s41586-026-10406-w
PMCID: PMC13149005

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The evolutionary history and unique genetic diversity of Indigenous Americans.PMID 42020734Read ↗

Patterns of Genetic Coding Variation in a Native American Population before and after European Contact.Semantic proximity Read ↗

Indigenous people from Amazon show genetic signatures of pathogen-driven selectionSemantic proximity Read ↗

A catalogue of early diverged contemporary human genome variation reveals distinct Khoe-San populations.Semantic proximity Read ↗

The Genetic Diversity of the Americas.Semantic proximity Read ↗

The genomic landscape of Mexican Indigenous populations brings insights into the peopling of the Americas.Semantic proximity Read ↗

Whole genome variation in 27 Mexican indigenous populations, demographic and biomedical insights.Semantic proximity Read ↗

The genomic impact of European colonization of the AmericasSemantic proximity Read ↗

The Peruvian Genome Project: expanding the global pool of genome diversity from South AmericaSemantic proximity Read ↗

Continental-scale genomic analysis suggests shared post-admixture adaptation in AmericasSemantic proximity Read ↗

Continental-scale genomic analysis suggests shared post-admixture adaptation in the Americas.Semantic proximity Read ↗

Peopling of the Americas as inferred from ancient genomics.Semantic proximity Read ↗

Early human dispersals within the Americas.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.