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Acute promyelocytic leukemia (APL): remaining challenges towards a cure for all

10 Nov 2019

Abstract excerpt

The application of all-trans retinoic acid (ATRA) and arsenic trioxide (ATO) has revolutionized the treatment of acute promyelocytic leukemia (APL). More than 80-90% of patients are expected to be cured with a combination of ATRA, ATO and/or chemotherapy. In this review, we focus on the remaining obstacles to a cure for all patients with APL. We review the issue of early death and coagulopathy and discuss the...

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PMID: 31842650
DOI: 10.1080/10428194.2019.1613540

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